The Baseline African Sepsis Incidence Survey (BASIS) is a study carried out at health facilities within 10 countries in sub-Saharan Africa, to better understand the burden of sepsis in Africa and better characterise case definitions.
The study will initiate a multi-country, short period observational study of sepsis related admissions in African hospitals. The study will a) provide an incidence and point-prevalence estimate of community-acquired sepsis in each of the 10 selected countries; b) collect data to inform evaluation of existing sepsis definitions and c) describe capability of sites to identify and treat sepsis.
The aims are the study are;
- Estimate incidence of sepsis among non-pregnant adults in sub-Saharan Africa utilizing prevalence and catchment area data from Burkina Faso, Cameroon, Democratic Republic of Congo, Ethiopia, Gabon, Ghana, Malawi, Nigeria, Sierra Leone, and Uganda
- Assess in-hospital mortality (censored at 2 weeks) and length of hospitalisation among non-pregnant adults with sepsis in sub-Saharan Africa
- Describe variation in prevalence and incidence estimates of sepsis in non-pregnant adults within Africa when applying different available sepsis definitions
- Assess the resources available and the burden of clinical work in hospitals providing care to patients with sepsis
BASIS will be completed over the course of two 7-day periods approximately six months apart. The 10 partners taking place are;
- Malawi – Jamie Rylance
- Uganda – Shevin Jacob and Sharon Nyegisa
- Burkina Faso – Armel Poda
- Cameroon – Bertrand Hugo Mbatchou Nghane
- Ethiopia – Dawit Kebede Huluka
- DRC – Patrick de Marie Katoto
- Ghana – John Adabie Appiah
- Nigeria – Michael Iroezindu
- Sierra Leone – Sulaiman Lakoh