Through a range of collaborations in Africa and Asia such as IntHEC we are leading research in the development and scale-up of large scale, complex interventions to prevent the spread of HIV and to improve Reproductive Health, HIV outcomes and service delivery especially amongst young people, adolescents and marginalised groups. We work with national and international policymakers in HIV testing and counselling to evaluate scale-up, strengthen quality assurance systems and develop strategy in a range of epidemic settings, bringing research findings directly into policy and practice globally.