Current Project: Accelerating malaria elimination efforts in Sudano-Sahelian region of Africa: elucidation of factors driving transmission and unravelling the molecular basis of insecticide resistance in the major malaria vectors.
Benjamin Menze; Jacob M Rivers; Sulaiman S Ibrahim; Helen Irving; Christophe Antonio-Nkondjio; Parfait H Awono-Ambene and Charles S. Wondji (2016). Multiple insecticide resistance in the malaria vector Anopheles funestus from northern Cameroon is mediated by metabolic resistance alongside potential target site insensitivity mutations. PloS ONE. PLoS One. 2016 Oct 10;11(10): e0163261. doi: 10.1371/journal.pone.0163261.
Jacob M Riveron; Michael Osae; Alexander Egyir-Yawson; Helen Irving; Sulaiman S Ibrahim; Charles S Wondji (2016) Multiple insecticide resistance in the major malaria vector Anopheles funestus in southern Ghana: implications for malaria control. Parasites & Vectors 9 (504). DOI 10.1186/s13071-016-1787-8.
Yayo A.M., Ado A., Habib A.G., Hamza M., Iliyasu Z., Sadeeq I.A., Ma’aruf Y.M., Musa K.A., Barodo M.M., Inuwa M.B., and Ibrahim S.S. (2016). Effectiveness of Transfluthrin-impregnated Insecticide (Paper Rambo) and Mechanical Screening Against Culicine and Anopheline Mosquito Vectors in Kumbotso, Kano, Nigeria, Mol Entomol 7(04): 1-8. doi: 10.5376/me.2016.07.0004
Intan Ishak., Jacob M. Riveron., Sulaiman S. Ibrahim., Helen Irving and Charles S. Wondji (2016). The Cytochrome P450 gene CYP6P12 confers pyrethroid resistance in kdr-free Malaysian populations of the dengue vector Aedes albopictus. Sci. Rep. 6, 24707; doi: 10.1038/srep24707.
Sulaiman S. Ibrahim., Miranda Ndula., Jacob M. Riveron., Helen Irving and Charles S. Wondji (2016). The P450 CYP6Z1 confers carbamate/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation. Mol Ecol DOI: 10.1111/mec.13673
Sulaiman S. Ibrahim., Jacob M. Riveron., Robert Stott., Helen Irving and Charles S. Wondji (2015). The cytochrome P450 CYP6P4 is responsible for the high pyrethroid resistance in knockdown resistance-free Anopheles arabiensis. Insect Biochem and Mol Biol. 68. pp23-32.doi:10.1016/j.ibmb.2015.10.015
Sulaiman S. Ibrahim., Jacob M. Riveron., Jaclyn Bibby., Helen Irving., Cristina Yunta., Mark J.I. Paine and Charles S. Wondji (2015) Allelic variation of cytochrome P450s drives resistance to bednet insecticides in a major malaria vector. PLoS Genet 11(10): e1005618. doi:10.1371/journal.pgen.1005618.
Jacob M. Riveron, Martin Chiumia, Benjamin D. Menze, Kayla G. Barnes, Helen Irving, Sulaiman S. Ibrahim, Gareth D. Weedall, Themba Mzilahowa and Charles S. Wondji (2015) Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control. Malar J, 2015, 14:344.
Jacob M. Riveron, Cristina Yunta, Sulaiman S. Ibrahim, Rousseau Djouaka, Helen Irving, Benjamin Menze, Hanafy Mohamed, Armando Albert and Charles S. Wondji (2013) A single mutation in the GSTe2 gene allows for tracking of metabolically based insecticide resistance in a major malaria vector. Genome Biol, 2014. 15 R:27
Sulaiman S. Ibrahim., Yayo A. Manu., Zainab Tukur., Helen Irving and Charles S. Wondji (2014) High frequency of kdr L1014F is associated with pyrethroid resistance in Anopheles coluzzi in Sudan Savanna of northern Nigeria. BMC Infec Dis, 2014 14:441.
Jacob M. Riveron†., Sulaiman S. Ibrahim†; Emmanuel Chanda., Themba Mzilahowa., Nelson Cuamba., Helen Irving., Kayla G. Barnes., Miranda Ndula and Charles S. Wondji (2014). The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa. BMC Genomics, 2014 15:817. † Sharing first co-authorship.
Benjamin Menze; Jacob M Rivers; Sulaiman S Ibrahim; Helen Irving; Christophe Antonio-Nkondjio; Parfait H Awono-Ambene and Charles S. Wondji (2016). Multiple insecticide resistance in the malaria vector Anopheles funestus from northern Cameroon is mediated by metabolic resistance alongside potential target site insensitivity mutations. PloS ONE. PLoS One. 2016 Oct 10;11(10): e0163261. doi: 10.1371/journal.pone.0163261.
Jacob M Riveron; Michael Osae; Alexander Egyir-Yawson; Helen Irving; Sulaiman S Ibrahim; Charles S Wondji (2016) Multiple insecticide resistance in the major malaria vector Anopheles funestus in southern Ghana: implications for malaria control. Parasites & Vectors 9 (504). DOI 10.1186/s13071-016-1787-8.
Yayo A.M., Ado A., Habib A.G., Hamza M., Iliyasu Z., Sadeeq I.A., Ma’aruf Y.M., Musa K.A., Barodo M.M., Inuwa M.B., and Ibrahim S.S. (2016). Effectiveness of Transfluthrin-impregnated Insecticide (Paper Rambo) and Mechanical Screening Against Culicine and Anopheline Mosquito Vectors in Kumbotso, Kano, Nigeria, Mol Entomol 7(04): 1-8. doi: 10.5376/me.2016.07.0004
Intan Ishak., Jacob M. Riveron., Sulaiman S. Ibrahim., Helen Irving and Charles S. Wondji (2016). The Cytochrome P450 gene CYP6P12 confers pyrethroid resistance in kdr-free Malaysian populations of the dengue vector Aedes albopictus. Sci. Rep. 6, 24707; doi: 10.1038/srep24707.
Sulaiman S. Ibrahim., Miranda Ndula., Jacob M. Riveron., Helen Irving and Charles S. Wondji (2016). The P450 CYP6Z1 confers carbamate/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation. Mol Ecol DOI: 10.1111/mec.13673
Sulaiman S. Ibrahim., Jacob M. Riveron., Robert Stott., Helen Irving and Charles S. Wondji (2015). The cytochrome P450 CYP6P4 is responsible for the high pyrethroid resistance in knockdown resistance-free Anopheles arabiensis. Insect Biochem and Mol Biol. 68. pp23-32.doi:10.1016/j.ibmb.2015.10.015
Sulaiman S. Ibrahim., Jacob M. Riveron., Jaclyn Bibby., Helen Irving., Cristina Yunta., Mark J.I. Paine and Charles S. Wondji (2015) Allelic variation of cytochrome P450s drives resistance to bednet insecticides in a major malaria vector. PLoS Genet 11(10): e1005618. doi:10.1371/journal.pgen.1005618.
Jacob M. Riveron, Martin Chiumia, Benjamin D. Menze, Kayla G. Barnes, Helen Irving, Sulaiman S. Ibrahim, Gareth D. Weedall, Themba Mzilahowa and Charles S. Wondji (2015) Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control. Malar J, 2015, 14:344.
Jacob M. Riveron, Cristina Yunta, Sulaiman S. Ibrahim, Rousseau Djouaka, Helen Irving, Benjamin Menze, Hanafy Mohamed, Armando Albert and Charles S. Wondji (2013) A single mutation in the GSTe2 gene allows for tracking of metabolically based insecticide resistance in a major malaria vector. Genome Biol, 2014. 15 R:27
Sulaiman S. Ibrahim., Yayo A. Manu., Zainab Tukur., Helen Irving and Charles S. Wondji (2014) High frequency of kdr L1014F is associated with pyrethroid resistance in Anopheles coluzzi in Sudan Savanna of northern Nigeria. BMC Infec Dis, 2014 14:441.
Jacob M. Riveron†., Sulaiman S. Ibrahim†; Emmanuel Chanda., Themba Mzilahowa., Nelson Cuamba., Helen Irving., Kayla G. Barnes., Miranda Ndula and Charles S. Wondji (2014). The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa. BMC Genomics, 2014 15:817. † Sharing first co-authorship.
Charles Mulamba., Jacob M. Riveron., Sulaiman S. Ibrahim., Helen Irving., Kayla G. Barnes., Louis G. Mukwaya., Josephine Birungi and Charles S. Wondji. (2014). Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms. PloS ONE, 2014 9 (10) e110058.
Jacob M. Riveron., Helen Irving., Miranda Ndula., Kayla G. Barnes., Sulaiman S Ibrahim., Mark J.I. Paine and Charles S. Wondji (2013) Directionally selected P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus. PNAS 110 (1): 252-257.
H. Irving., JM Riveron., SS Ibrahim., NF Lobo and CS Wondji (2012) Positional cloning of rp2 QTL associates the P450 genes CYP6Z1, CYP6Z3 and CYP6M7 with pyrethroid resistance in the malaria vector Anopheles funestus. Heredity, 2012, 109:383-392.
Peer-Reviewed Articles
Amen N. Fadel†, Sulaiman S. Ibrahim†, Magellan Tchouakui, Ebai Terence, Murielle J. Wondji, Micareme Tchoupo, Samuel Wanji, Charles S. Wondji. A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of Cameroon. Parasites and Vectors 2019. 12 (263). https://doi.org/10.1186/s13071-019-3523-7. † Contributed equally
Sulaiman S. Ibrahim, Muhammad M Mukhtar, Helen Irving, Rabiou Labbo, Michael O. Kusimo, Izamné Mahamadou, Charles S Wondji. High Plasmodium infection and multiple insecticide resistance in a major malaria vector Anopheles coluzzii from Sahel of Niger Republic. Malaria Journal 2019. 18 (181). https://doi.org/10.1186/s12936-019-2812-0
Sulaiman S. Ibrahim, Muhammad M. Mukhtar, Jamila A. Datti, Helen Irving, Michael O. Kusimo, Williams Tchapga, Nura Lawal, Fatima I. Sambo and Charles S. Wondji. Temporal escalation of Pyrethroid Resistance in the major malaria vector Anopheles coluzzii from Sahelo-Sudanian Region of northern Nigeria. Scientific Reports 2019. 9:7395 (2019). https://doi.org/10.1038/s41598-019-43634-4
Gareth D. Weedall, Leon M. J. Mugenzi, Benjamin D. Menze, Magellan Tchouakui, Sulaiman S. Ibrahim, Nathalie Amvongo-Adjia, Helen Irving, Murielle J. Wondji, Micareme Tchoupo, Rousseau Djouaka, Jacob M. Riveron and Charles S. Wondji. A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy. 2019, 11 (484); DOI: 10.1126/scitranslmed.aat7386
Bala, I.; Mukhtar, M.M.; Saka, H.K.; Abdullahi, N.; Ibrahim, S.S. Determination of Insecticide Susceptibility of Field Populations of Tomato Leaf Miner (Tuta absoluta) in Northern Nigeria. Agriculture 2019, 9 (7). https://doi.org/10.3390/agriculture9010007
Sulaiman S. Ibrahim, Nathalie Amvongo-Adjia, Murielle J. Wondji, Helen Irving, Jacob M. Riveron and Charles S. Wondji (2018). Pyrethroid resistance in the major malaria vector Anopheles funestus is exacerbated by overexpression and overactivity of the P450 CYP6AA1 across Africa. Genes 2018, 9(3), 140; https://doi.org/10.3390/genes9030140
Jacob M. Riveron; Sulaiman S. Ibrahim, Charles Mulamba, Rousseau Djouaka, Helen Irving, Murielle J. Wondji, Intan H. Ishak and Charles S. Wondji (2017). Genome-wide transcription and functional analyses reveal heterogeneous molecular mechanisms driving pyrethroids resistance in the major malaria vector Anopheles funestus across Africa. G3 (Bethesda): Genes|Genomes|Genetics 2017 7;7(6):1819-1832. doi: https://doi.org/10.1534/g3.117.040147
Benjamin Menze; Jacob M Rivers; Sulaiman S. Ibrahim; Helen Irving; Christophe Antonio-Nkondjio; Parfait H Awono-Ambene and Charles S. Wondji (2016). Multiple insecticide resistance in the malaria vector Anopheles funestus from northern Cameroon is mediated by metabolic resistance alongside potential target site insensitivity mutations. PloS ONE. 11(10): e0163261. https://doi.org/10.1371/journal.pone.0163261
Intan H Ishak; Basile Kamgang; Sulaiman S. Ibrahim; Jacob M Riveron; Helen Irving; Charles S. Wondji (2017). Pyrethroid resistance in Malaysian populations of dengue vector Aedes aegypti is mediated by CYP9 family of cytochrome P450 genes. PLoS Negl Trop Dis 11(1): e0005302. https://doi.org/10.1371/journal.pntd.0005302
Jacob Riveron; Michael Osae; Alexander Egyir-Yawson; Helen Irving; Sulaiman S. Ibrahim; Charles S Wondji (2016). Multiple insecticide resistance in the major malaria vector Anopheles funestus in southern Ghana: implications for malaria control. Parasites & Vectors 9 (504). DOI 10.1186/s13071-016-1787-8.
Yayo A.M., Ado A., Habib A.G., Hamza M., Iliyasu Z., Sadeeq I.A., Ma’aruf Y.M., Musa K.A., Barodo M.M., Inuwa M.B., and Ibrahim S.S. (2016). Effectiveness of Transfluthrin-impregnated Insecticide (Paper Rambo) and Mechanical Screening Against Culicine and Anopheline Mosquito Vectors in Kumbotso, Kano, Nigeria, Mol Entomol 7(04): 1-8. doi: 10.5376/me.2016.07.0004
Intan Ishak., Jacob M. Riveron., Sulaiman S. Ibrahim., Helen Irving and Charles S. Wondji (2016). The Cytochrome P450 gene CYP6P12 confers pyrethroid resistance in kdr-free Malaysian populations of the dengue vector Aedes albopictus. Sci. Rep. 6, 24707; doi: 10.1038/srep24707.
Sulaiman S. Ibrahim., Miranda Ndula., Jacob M. Riveron., Helen Irving and Charles S. Wondji (2016). The P450 CYP6Z1 confers carbamate/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation. Mol Ecol DOI: 10.1111/mec.13673
Sulaiman S. Ibrahim., Jacob M. Riveron., Robert Stott., Helen Irving and Charles S. Wondji (2015). The cytochrome P450 CYP6P4 is responsible for the high pyrethroid resistance in knockdown resistance-free Anopheles arabiensis. Insect Biochem and Mol Biol. 68. pp23-32. doi:10.1016/j.ibmb.2015.10.015
Sulaiman S. Ibrahim., Jacob M. Riveron., Jaclyn Bibby., Helen Irving., Cristina Yunta., Mark J.I. Paine and Charles S. Wondji (2015). Allelic variation of cytochrome P450s drives resistance to bednet insecticides in a major malaria vector. PLoS Genet 11(10): e1005618. doi:10.1371/journal.pgen.1005618.
Jacob M. Riveron, Martin Chiumia, Benjamin D. Menze, Kayla G. Barnes, Helen Irving, Sulaiman S. Ibrahim, Gareth D. Weedall, Themba Mzilahowa and Charles S. Wondji (2015). Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control. Malar J, 2015, 14:344. DOI 10.1186/s12936-015-0877-y
Jacob M. Riveron, Cristina Yunta, Sulaiman S. Ibrahim, Rousseau Djouaka, Helen Irving, Benjamin Menze, Hanafy Mohamed, Armando Albert and Charles S. Wondji (2013). A single mutation in the GSTe2 gene allows for tracking of metabolically based insecticide resistance in a major malaria vector. Genome Biol, 2014. 15 R:27. DOI: 10.1186/gb-2014-15-2-r27
Sulaiman S. Ibrahim., Yayo A. Manu., Zainab Tukur., Helen Irving and Charles S. Wondji (2014). High frequency of kdr L1014F is associated with pyrethroid resistance in Anopheles coluzzi in Sudan Savanna of northern Nigeria. BMC Infec Dis, 2014 14:441. DOI: 10.1186/1471-2334-14-441
Jacob M. Riveron†., Sulaiman S. Ibrahim†; Emmanuel Chanda., Themba Mzilahowa., Nelson Cuamba., Helen Irving., Kayla G. Barnes., Miranda Ndula and Charles S. Wondji (2014). The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa. BMC Genomics, 2014 15:817. DOI: 10.1186/1471-2164-15-817. † Contributed equally.
Charles Mulamba., Jacob M. Riveron., Sulaiman S. Ibrahim., Helen Irving., Kayla G. Barnes., Louis G. Mukwaya., Josephine Birungi and Charles S. Wondji. (2014). Widespread pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms. PloS ONE, 2014 9 (10) e110058. doi:10.1371/journal.pone.0110058
Jacob M. Riveron., Helen Irving., Miranda Ndula., Kayla G. Barnes., Sulaiman S Ibrahim., Mark J.I. Paine and Charles S. Wondji (2013). Directionally selected P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus. PNAS 110 (1): 252-257. doi: 10.1073/pnas.1216705110
H. Irving., JM Riveron., SS Ibrahim., NF Lobo and CS Wondji (2012). Positional cloning of rp2 QTL associates the P450 genes CYP6Z1, CYP6Z3 and CYP6M7 with pyrethroid resistance in the malaria vector Anopheles funestus. Heredity, 2012, 109:383-392. doi:10.1038/hdy.2012.53
Ibrahim, S.S. and Wudil, A.M. (2011). Effect of metronidazole administration on serum electrolytes and acetaldehyde in rats treated with smokeless tobacco. BEST Journal 8(3): 83-85.
Atiku, M.K., Ibrahim, S. S., Khelpai, D.G. and Ubom, G.A. (2005) Preliminary study on the effects of V. amygdalina, A. millocolifolium and G. sylvestre on serum glucose, total cholesterol and total protein in normoglycemic rats. BEST Journal 2(1): 33-34.