Dr Pat Pignatelli

Senior technician

BSc genetic and MPhil genetics, University of Edinburgh. Background working in population genetics at Edinburgh university until 1999.

Research: Molecular biology of Insecticide resistance. Teaching and technical support to both students and overseas visitors.

Selected publications

  • Cross-resistance profiles of malaria mosquito P450s associated with pyrethroid resistance against WHO insecticides YuntaYanes, Cristina, Hemmings, Kay, Stevenson, Bradley, Koekemoer, Lizette L., Matambo, Tonderi, Pignatelli, Patricia, Voice, Michael, Nász, Szilárd and Paine, Mark ORCID: https://orcid.org/0000-0003-2061-7713 (2019) Cross-resistance profiles of malaria mosquito P450s associated with pyrethroid resistance against WHO insecticides'. Pesticide Biochemistry and Physiology, Vol 161, pp. 61-67.

    Insecticide resistance levels and mechanisms in Aedes aegypti populations in and around Ouagadougou, Burkina Faso. Badolo, Athanase, Sombié, Aboubacar, Pignatelli, Patricia, Sanon, Aboubakar, Yaméogo, Félix, Wangrawa, Dimitri W, Sanon, Antoine, Kanuka, Hirotaka, McCall, Philip ORCID: https://orcid.org/0000-0002-0007-3985 and Weetman, David ORCID: https://orcid.org/0000-0002-5820-1388 (2019) 

    Insecticide resistance levels and mechanisms in Aedes aegypti populations in and around Ouagadougou, Burkina Faso.'. PLoS Neglected Tropical Diseases, Vol 13, Issue 5, e0007439. The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae. Ingham, Victoria ORCID: https://orcid.org/0000-0001-5708-4741 , Pignatelli, Patricia, Moore, Jonathan D, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537 and Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247 (2017) 'The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae.'. BMC Genomics, Vol 18, Issue 1, p. 669.

    The Anopheles gambiae ABC transporter family: phylogenetic analysis and tissue localisation provide clues on function and role in insecticide resistance. Pignatelli, Patricia, Ingham, Victoria ORCID: https://orcid.org/0000-0001-5708-4741 , Balabanidou, Vasileia, Vontas, John, Lycett, Gareth ORCID: https://orcid.org/0000-0002-2422-053X and Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247 (2018)

    The Anopheles gambiae ABC transporter family: phylogenetic analysis and tissue localisation provide clues on function and role in insecticide resistance.'. Insect Molecular Biology, Vol 27, Issue 1, pp. 110-122.

    Pyriproxyfen is metabolized by P450s associated with pyrethroid resistance in An. gambiae. YuntaYanes, Cristina, Grisales, Nelson, Nász, Szilárd, Hemmings, Kay, Pignatelli, Patricia, Voice, Michael, Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247 and Paine, Mark ORCID: https://orcid.org/0000-0003-2061-7713 (2016) 'Pyriproxyfen is metabolized by P450s associated with pyrethroid resistance in An. gambiae.'. Insect biochemistry and molecular biology, Vol 78, pp. 50-57.