Dr Joseph Okebe

Senior Research Associate

Joseph Okebe has a medical degree from the University of Nigeria and completed his clinical specialty training in Paediatrics with the West African College of Physicians. He obtained an MSc in Public Health from the London School of Hygiene & Tropical Medicine, and a PhD in Medical Sciences from the University of Antwerp, Antwerp, Belgium.

He joined the UK’s Medical Research Council Unit in The Gambia and worked across a range of studies focused on malaria control interventions. In his 14 years at the MRCG, he moved from a research clinician to leading clinical trials evaluating interventions targeting malaria elimination. He was a co-investigator on trials evaluating efficacy and safety of primaquine for asymptomatic gametocyte carriers and, cluster trials assessing the impact of reactive treatment of asymptomatic populations on residual plasmodium falciparum carriage in The Gambia.

He has acquired extensive experience in supporting guideline reviews on malaria control and working with regional and national health managers.

He joins the International Public Health Department as a Senior Research Associate and will play a central role in research evaluating different ways of preventing and managing HIV-infection and non-communicable diseases in Africa. As part of this role he will provide support on clinical trials and large public health research studies in Tanzania and Uganda.

Selected publications

  • Ravinetto R, Tinto H, Diro E, Okebe J, Mahendradhata Y, Rijal S, Gotuzzo E, Lutumba P, Nahum A, De Nys K, Casteels M, Boelaert M. It is time to revise the international Good Clinical Practices guidelines: recommendations from non-commercial North-South collaborative trials. BMJ Glob Health. 2016 Nov 16;1(3):e000122.

    Okebe J, Affara M, Correa S, Muhammad AK, Nwakanma D, Drakeley C, D'Alessandro U. School-based countrywide seroprevalence survey reveals spatial heterogeneity in malaria transmission in the Gambia. PLoS One. 2014 Oct 22;9(10):e110926.

    Okebe J, Eisenhut M. Pre-referral rectal artesunate for severe malaria. Cochrane Database Syst Rev. 2014 May 29;(5):CD009964.

    Jaiteh F, Masunaga Y, Okebe J, D'Alessandro U, Balen J, Bradley J, Gryseels C, Ribera JM, Grietens KP. Community perspectives on treating asymptomatic infections for malaria elimination in The Gambia. Malar J. 2019 Feb 18;18(1):39.

    Taylor WR, Naw HK, Maitland K, Williams TN, Kapulu M, D'Alessandro U, Berkley  JA, Bejon P, Okebe J, Achan J, Amambua AN, Affara M, Nwakanma D, van Geertruyden  JP, Mavoko M, Lutumba P, Matangila J, Brasseur P, Piola P, Randremanana R, Lasry
    E, Fanello C, Onyamboko M, Schramm B, Yah Z, Jones J, Fairhurst RM, Diakite M, Malenga G, Molyneux M, Rwagacondo C, Obonyo C, Gadisa E, Aseffa A, Loolpapit M, Henry MC, Dorsey G, John C, Sirima SB, Barnes KI, Kremsner P, Day NP, White NJ, Mukaka M. Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa. BMC Med. 2018 Jan 18;16(1):11.

    Bastiaens GJH, Tiono AB, Okebe J, Pett HE, Coulibaly SA, Gonçalves BP, Affara  M, Ouédraogo A, Bougouma EC, Sanou GS, Nébié I, Bradley J, Lanke KHW, Niemi M, Sirima SB, d'Alessandro U, Bousema T, Drakeley C. Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials. PLoS One. 2018 Jan 11;13(1):e0190272.

    Amambua-Ngwa A, Okebe J, Mbye H, Ceesay S, El-Fatouri F, Joof F, Nyang H, Janha R, Affara M, Ahmad A, Kolly O, Nwakanma D, D'Alessandro U. Sustained Ex Vivo Susceptibility of Plasmodium falciparum to Artemisinin Derivatives but Increasing Tolerance to Artemisinin Combination Therapy Partner Quinolines in The Gambia. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00759-17.

    Okebe J, Bousema T, Affara M, Di Tanna GL, Dabira E, Gaye A, Sanya-Isijola F,  Badji H, Correa S, Nwakanma D, Van Geertruyden JP, Drakeley C, D'Alessandro U. The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial. EBioMedicine. 2016 Nov;13:348-355.

    Neuberger A, Okebe J, Yahav D, Paul M. Oral iron supplements for children in malaria-endemic areas. Cochrane Database Syst Rev. 2016 Feb 27;2:CD006589.

    Ceesay SJ, Koivogui L, Nahum A, Taal MA, Okebe J, Affara M, Kaman LE, Bohissou F, Agbowai C, Tolno BG, Amambua-Ngwa A, Bangoura NF, Ahounou D, Muhammad AK, Duparc S, Hamed K, Ubben D, Bojang K, Achan J, D'Alessandro U. Malaria Prevalence among Young Infants in Different Transmission Settings, Africa. Emerg  Infect Dis. 2015 Jul;21(7):1114-21.