Dr David Adedapo Ishola

Senior Clinical Lecturer

David combines academic work at LSTM with his health service role as a public health physician at the national public health agency in Wales (Consultant Epidemiologist, Communicable Disease Surveillance Centre, Public Health Wales NHS Trust).

Clinical and public health background: David qualified in medicine in Nigeria (Obafemi Awolowo University, Ile-Ife) and specialised in internal medicine (FWACP, West Africa), before UK specialist training in public health medicine in Liverpool, Lancashire, and London. Since 2012, he has worked in both full-time and honorary consultant roles with Public Health England (now UKHSA), and currently Public Health Wales.

Research training and experience: He obtained a PhD at Utrecht University (Netherlands), followed by postdoctoral health protection research at UCL and PHE Colindale; and field team leadership in global public health research at LSHTM (coordinating multi-partner Ebola vaccine trials, leading a capacity building programme, and managing health systems engagement in Sierra Leone, 2015-2021).

Medical and public health teaching: David has taught public health and clinical subjects at postgraduate and undergraduate level, including experience with curriculum development and course leadership; across different resource settings (high and low-income); and using different mediums (in person and virtual).

Teaching

David's role has a remit as the LSTM clinical professional lead on public health education - including developing public health teaching; overseeing NHS public health specialist training placements at the School; and fostering both UK and overseas partnerships on public health education and scholarship. This will involve seeking to build local and global networks for public health education, CPD, capacity building, and research.

David teaches on the following courses:
Master of Public Health (MPH): Programme Director (joint)
MPH Module TROP720 (Outbreak Control and Health Protection): Module Convenor
MPH Module TROP713 (Public Health Approaches to Modern Epidemics): Module co-Convenor
Diploma in Tropical Medicine & Hygiene (DTM&H): Public health
Diploma in Tropical Nursing (DTN): Public health
BSc Module LIFE357 (Advanced Skills in Tropical Disease Biology): Clinical trials
Educational Supervisor for LSTM-based NHS public health specialists-in-training (Specialty Registrars)

Other relevant expertise, professional memberships, awards

FFPH (Fellow of the Faculty of Public Health), UK Royal Colleges of Physicians
FWACP (Fellow of the West African College of Physicians)
FRCP(Glasg) (Fellow of the Royal College of Physicians and Surgeons of Glasgow)
FRSPH (Fellow, Royal Society of Public Health)
AFHEA (Associate Fellow, UK Higher Education Academy)
MFMLM (Member, Faculty of Medical Leadership & Management), UK Royal Colleges of Physicians
Member, Faculty of Remote, Rural & Humanitarian Healthcare, Royal College of Surgeons (Ed)

Selected publications

  • Ishola D, Manno D, Afolabi MO, et al. Safety and long-term immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Sierra Leone: a combined open-label, non-randomised stage 1, and a randomised, double-blind, controlled stage 2 trial. Lancet Infect Dis. 2022; 22(1):97-109. doi: 10.1016/S1473-3099(21)00125-0. PMID: 34529963

    Afolabi MO, Ishola D, Manno D, et al. Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in children in Sierra Leone: a randomised, double-blind, controlled trial. Lancet Infect Dis. 2022; 22(1):110-122. doi: 10.1016/S1473-3099(21)00128-6. PMID: 34529962

    Ishola D; EBOVAC-Salone Malaria Infection (MALI) Sub-Study Team. Asymptomatic Malaria Infection and the Immune Response to the 2-Dose Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccine Regimen in Adults and Children. Clin Infect Dis. 2022:ciac209. doi: 10.1093/cid/ciac209. Online ahead of print. PMID: 35640636

    Manno D, Ayieko P, Ishola D, et al. Ebola Virus Glycoprotein IgG Seroprevalence in Community Previously Affected by Ebola, Sierra Leone. Emerg Infect Dis. 2022; 28(3):734-738. doi: 10.3201/eid2803.211496. PMID: 35202536

    Adetola HH, Ishola D, Afolabi MO, et al. Clinical presentations and management of COVID-19 infected children seen in a district health facility in Kambia, northern Sierra Leone. Pan Afr Med J. 2020; 37(Suppl 1):28. doi: 10.11604/pamj.supp.2020.37.28.26312. eCollection 2020. PMID: 33456652

    Baiden F, Fleck S, Leigh B, Ayieko P, Tindanbil D, Otieno T, Lawal B, Tehtor M, Rogers M, Odeny L, Hodges MH, Sonnie M, Samai M, Ishola D, Lowe B, Watson-Jones D, Greenwood B. Prevalence of malaria and helminth infections in rural communities in northern Sierra Leone, a baseline study to inform Ebola vaccine study protocols. PLoS One. 2022;17(7):e0270968. doi: 10.1371/journal.pone.0270968. eCollection 2022. PMID: 35793331

    Mooney T, Smout E, Leigh B, Greenwood B, Enria L, Ishola D, Manno D, Samai M, Douoguih M, Watson-Jones D. EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country. Clin Trials. 2018; 15(5):436-443. doi: 10.1177/1740774518780678. PMID: 29895178

    Ishola DA, Andrews N, Waight P, et al. Randomized Trial to Compare the Immunogenicity and Safety of a CRM or TT Conjugated Quadrivalent Meningococcal Vaccine in Teenagers who Received a CRM or TT Conjugated Serogroup C Vaccine at Preschool Age. Pediatr Infect Dis J. 2015; 34(8):865-74. doi: 10.1097/INF.0000000000000750. PMID: 26075813

    Tengbeh AF, Enria L, Smout E, Mooney T, Callaghan M, Ishola D, Leigh B, Watson-Jones D, Greenwood B, Larson H, Lees S. "We are the heroes because we are ready to die for this country": Participants' decision-making and grounded ethics in an Ebola vaccine clinical trial. Soc Sci Med. 2018 Apr;203:35-42. doi: 10.1016/j.socscimed.2018.03.008. PMID: 29544144

    Fragaszy E, Ishola DA, Brown IH, et al. Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort. Influenza Other Respir Viruses. 2016 Jul;10(4):291-300. doi: 10.1111/irv.12364. Epub 2016 Jan 29. PMID: 26611769