Dr Morton has worked as a consultant in critical care medicine at Aintree University Hospital since 2016. He has been associated with LSTM since 2013, working initially as a clinical research associate and appointed as a senior clinical lecturer in May 2019. Dr Morton was awarded his doctorate (MD) in 2016.
Experimental Human Pneumococcal Carriage (EHPC): Dr Morton is working with Professor Stephen Gordon to transfer standardised and safe operating procedures from the established EHPC programme at LSTM to establish the first controlled human infection model in Malawi. This platform will be used to test pneumococcal vaccine candidate choices in an at-risk population who stand the most to gain from new and improved vaccine strategies.
Immunomodulatory therapies for sepsis: Dr Morton is working with industrial and academic collaborators to develop and deliver a first in human clinical trial to determine the safety, pharmacokinetics and pharmacodynamics of P4 peptide. P4 is a naturally occurring immunomodulatory peptide that upregulates phagocytic function to better ingest and kill pathogenic bacteria.
Pathophysiology of sepsis: Dr Morton is particularly interested how neutrophil function and dysfunction predisposes patients to sepsis and poor outcomes. He has multiple academic and clinical collaborations and observational clinical studies in progress. Current projects include measurement of neutrophil function in moderate and severe community acquired pneumonia and before and after cytotoxic chemotherapy for oncological conditions.
Pragmatic Interventions to improve acute care outcomes: Dr Morton collaborates with clinical, academic and industrial partners to explore and implement interventions to improve outcomes after acute illness presentations to hospital. Current projects include evaluation of a sepsis biomarker point of care device, measures to improve difficult airway management in anaesthesia and determinants of long-term outcome following critical care admission.
PhD supervisor to Wanjiku Kagima, Brenda Mungai, Mohammed Alsabani and Samar Alosaimi
- Fellow of the Royal College of Anaesthetists (FRCA)
- Fellow of the Faculty of Intensive Care Medicine (FFICM)