Professor Tanya Parish

Research interests

My research is focused in two main areas: (i) understanding the biology of the global pathogen Mycobacterium tuberculosis; and (ii) discovering and developing novel drugs for tuberculosis that are effective at curing drug sensitive and drug resistant tuberculosis.

My fundamental research addresses mechanisms of antibiotic resistance, the mode of action of antibiotics and the investigation of essential cellular processes in mycobacteria.

My applied work encompasses a range of early-stage drug discovery including assay development and high throughput screening, drug target identification and validation, and medicinal and synthetic chemistry.

Selected research publications

Common Biological Properties of Mycobacterium tuberculosis MmpL3 Inhibitors – Journal: ACS Infectious Diseases – Published: 19th August 2025

Novel 3-Aminothieno[2,3-b]pyridine-2-carboxamides with Activity against Mycobacterium tuberculosis – Journal: ACS Medicinal Chemistry Letters – Published: 13th February 2025

Deep learning–driven bacterial cytological profiling to determine antimicrobial mechanisms in Mycobacterium tuberculosis – Journal: Proceedings of the National Academy of Sciences of the United States of America – Published: 11th February 2025

8-Hydroxyquinoline Series Exerts Bactericidal Activity against Mycobacterium tuberculosis Via Copper-Mediated Toxicity – Journal: ACS Infectious Diseases – Published: 27th September 2024

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