Dr Rosemary Lees
- Principal Research Associate, Vector Biology
Biography
Rosemary Lees studied Biological Sciences at Warwick University, and received a doctorate in Zoology from Jesus College, Oxford in 2008. Her thesis focused on developing transgenic strains of Aedes aegypti for vector control, then analysing their induced gene expression and phenotype and assessing the competitiveness of larvae and of adult males. This interest in male mating biology developed during a Framework Programme 7 Marie Curie Fellowship looking at proxy indicators of mating success in the mosquitoes that transmit malaria, and informed later work developing and overseeing sterile insect technique projects for mosquito control in various parts of the world for the United Nations International Atomic Energy Agency.
Research interests
Rosemaryβs research group looks to identify issues with the methods used in the development and evaluation of insecticides and mosquito control tools and then seeks to address these gaps through the development of consensus protocols, experimental validation of new and existing methods. In discussion with stakeholders they work to map out key areas of concern and generate consensus on solutions. Consensus building around standardised methodologies is important to increase the robustness of data and improve decision making for deployment of vector control tools.
She is also interested in insecticide resistance mechanisms and their impacts on vector control, and works with industry partners to screen and evaluate the potential of new insecticides, formulations and products as well as application equipment and related technologies designed to overcome resistance. There is a demand for novel behavioural assays to investigate novel, non-lethal effects of insecticides alongside the traditional methods for measuring mortality after exposure.
For example, with new products coming to market which rely on volatile insecticides to repel and kill mosquitoes the group is working to develop and standardise a novel method to monitor resistance to volatile insecticides. These new methods will be critical in collecting baseline data and then monitoring for resistance in mosquito populations in study sites where new spatial repellent tools are being evaluated.
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Teaching
Rosemary’s research group regularly hosts MSc and MRes project students and enbales them to work in an applied field on research with a very clear pathway to impact.Β
Selected research publications
The mini chamber test: a novel bioassay for bioefficacy testing of chlorfenapyr treated nets used in malaria control – Journal: Gates Open Research – Published: 1st May 2026
Maximising power with the minimum number of mosquitoes: Designing robust sample sizes for the WHO Cone Bioassay – Journal: Gates Open Research – Published: 27th August 2025
The Ξ²-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake – Journal: Parasites and Vectors – Published: 31st July 2025
Better methods, better data: landscaping the priorities for improving methodologies in vector control – Journal: Gates Open Research – Published: 28th July 2025
Unpacking WHO and CDC Bottle Bioassay Methods: A Comprehensive Literature Review and Protocol Analysis Revealing Key Outcome Predictors – Journal: Gates Open Research – Published: 18th December 2024
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