Selected research publications
Machine learning-driven identification of serotype-independent pneumococcal vaccine candidates using samples from human infection challenge studies – Journal: Vaccine – Published: 7th March 2026
The effect of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine on nasopharyngeal colonisation following human infection challenge with serotype 3 and serotype 6B (PREVENTING PNEUMO 2): a double-masked, randomised, controlled, phase 4 trial – Journal: The Lancet Microbe – Published: 13th February 2026
Protocol for a phase IV, Experimental Human Pneumococcal Challenge (EHPC) model to investigate Streptococcus pneumoniae serotype 3 (SPN3) colonisation following PCV15, a double-blind randomised controlled trial in healthy participants aged 18–50 years in the UK (RATIONALE-15) – Journal: BMJ Open – Published: 24th November 2025
Understanding the interaction of upper respiratory tract infection with respiratory syncytial virus and Streptococcus pneumoniae using a human challenge model a multicenter, randomized controlled study protocol – Journal: PLoS ONE – Published: 1st July 2025
Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial – Journal: The Lancet – Published: 1st January 2022
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