Biography
Gareth Lycett was born in Mpraeso, Ghana before moving to England and going to school in Birmingham. He was trained in biochemistry at Surrey University (BSc) and completed his PhD with a focus on molecular genetics at Liverpool School of Tropical Medicine (LSTM). Gareth then took post-doctoral and fellowship positions at the Institute of Parasitology, University of Rome, the Institute of Molecular Biology and Biotechnology in Crete, and the European Molecular Biology Laboratory in Heidelberg, Germany. He then took up a fellowship position back at LSTM, moving to tenure track and subsequently a faculty position in 2011.
Research interests
Gareth is a vector molecular biologist whose main interests are focused on functional genetic analysis of mosquitoes in relation to insecticide resistance and malaria transmission. Topics he has explored include cellular and molecular analysis of mosquito/plasmodium interactions, developing tools for conditional expression in transgenic anophelines, tissue specific regulation of gene expression in mosquitoes, and functional genetic analysis of insecticide resistance.
His team have developed routine analysis of gene function in anopheles through piggyBac transformation, PhiC31 mediated cassette exchange, Gal4/UAS, enhancer trapping and CRISPR/Cas9 methodology.
Teaching
Gareth undertakes practical and small group teaching on vector biology in Postgraduate Masters and Diploma Courses at LSTM.
He is a module coordinator on the MSc course Tropical Disease Biology and teaches on the biannual Diploma in Tropical Medicine and Hygiene course, in addition to supervision of MSc students for their projects.
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Selected research publications
Predictive chemoproteomics and functional validation reveal Coeae6g-mediated insecticide cross-resistance in the malaria vector Anopheles gambiae – Journal: Nature Communications – Published: 28th November 2025
A biocompatible supramolecular hydrogel mesh for sample stabilization in light microscopy and nanoscopy – Journal: Scientific Reports – Published: 25th November 2024
A Synthetic Biology Approach to Transgene Expression in Insects – Journal: ACS Synthetic Biology – Published: 28th August 2024
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae – Journal: Open Biology – Published: 24th July 2024
Aedes aegypti CCEae3A carboxylase expression confers carbamate, organophosphate and limited pyrethroid resistance in a model transgenic mosquito – Journal: PLoS Neglected Tropical Diseases – Published: 20th February 2024
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