Dr Rohit Patel

Biography

After obtaining a BSc in Neuroscience from the University of Manchester Rohit Patel completed MRes and PhD degrees at the University of Nottingham specialising in neuropharmacology. He joined the Centre for Snakebite Research & Interventions at the Liverpool School of Tropical Medicine in 2020 as a postdoctoral research associate and works under Prof Nicholas Casewell and Dr Cassandra Modahl.

Research interests

Rohit’s research involves investigating neurotoxic snake venom toxins from the ‘three-finger toxin’ family to find out what the most medically important toxins are and how they function. These toxins mainly target the nicotinic acetylcholine receptor at the neuromuscular junction to cause muscular paralysis. Inhibitors of these toxins are also assessed to determine their potential as treatments for neurotoxic snakebite. His interests also lie in investigating the mechanisms of action of toxins and other agents that cause neuronal damage.

Selected research publications

Practical progress towards the development of recombinant antivenoms for snakebite envenoming – Journal: Expert Opinion on Drug Discovery – Published: 29th April 2025

Plug and play virus-like particles for the generation of anti-toxin antibodies – Journal: Toxicon: X – Published: 29th August 2024

Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins – Journal: Science Translational Medicine – Published: 21st February 2024

Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL – Journal: Scientific Reports – Published: 8th December 2023

An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules – Journal: Biochemical Pharmacology – Published: 20th August 2023

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