Page 25 - LSTM_AnnualReport1415

LSTM Annual
Report 2014/15

The collaboration in Kenya also received a new grant from Respiratory research, household air pollution and

Norway’s Research Council to study the impact of monthly chronic lung disease
malaria chemoprevention in the management of severe
Our respiratory research group continues to expand. The team,
anaemia after discharge from hospital. The study will involve led by Dr Daniela Ferreira, secured grants for pneumococcal
2,200 children in 7 hospitals in Uganda and Kenya.
research from the Bill and Melinda Gates Foundation (BMGF)
We are also developing interventions of novel therapeutic and the MRC and completed a vaccine e cacy trial in

feeds to reduce intestinal in ammation in children with partnership with the Royal Liverpool and Broadgreen University
complicated severe acute malnutrition in Blantyre with funding Hospitals. The group launched the Experimental Human
Pneumococcal Carriage (EHPC) consortium with over 30 world
from MRC, Wellcome Trust and DFID. Working with Alder Hey
Children’s Hospital, Professor Stephen Allen is expanding our experts in pneumococcal research and continued its public
engagement and volunteer recruitment activities. The group
research in gastroenterology, hepatology and nutrition and
supporting the development of the hospital’s global health will also expand its work on mucosal immunity to examine how
programme.
nasal immune responses correlate with those in the lung, and

how these responses are a ected by inhaled particulates.
This year has seen a revision of our teaching provision
in paediatrics. Students are taken from the problems of Air pollution in homes caused by smoke from dirty-burning
fuels for cooking, heating and lighting causes four million
adolescent attending ante-natal clinics, delivery, post-natal care preventable deaths every year. Our ongoing trials, led by
and the management of sick and vulnerable children. Modules
Dr Kevin Mortimer, saw a ministerial visit from DFID. BBC’s
on hot topics in child health now take an evidence and quality science correspondent Victoria Gill travelled to Malawi to
improvement perspective.
cover the MRC, Wellcome Trust and DFID funded Cooking
And Pneumonia Study (CAPS), resulting in widespread UK and

international coverage. CAPS received further grants from the A healthy volunteer being inoculated
Wellcome Trust and BMGF. Our projects in Malawi are yielding with Pneumococcal bacteria in the nose
new insights into the burden of lung disease. Initial ndings

indicate that over 40% of adults around Blantyre have abnormal
lung function and we are developing approaches to prevent

and treat it.

Our MRC funded BREATHE-Africa Partnership, goes from
strength to strength and has now held two productive Annual

Meetings and trained a further 50 African doctors and scientists
in lung health and household air pollution research methods.

Tuberculosis

Tuberculosis (TB) disproportionately a ects the poor and

vulnerable, especially in developing countries, with millions of
new TB cases each year. Our department continues therefore

to have a strong research portfolio: from research synthesis
to health systems and policies. These are described in the TB
feature of this report.

A young child participating in the Cooking
And Pneumonia Study has her blood carbon
monoxide and oxygen levels measured

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